Second, how can we better identify immuno-modulating treatment principles tested in animal models to be suited for further translational clinical evaluation?
Further studies employing multivariate analysis and modeling of in vivo measurements will be useful for discriminating a subset of biologically relevant information from larger data sets, particularly in the setting of translational studies and evaluation of drugs for therapeutic efficacy endpoints.
The objective of our study was to explore the scope and issues of translational research relevant to evaluation, explore the views of researchers on the evaluation of oncological translational research, and select indicators measuring the outcomes and outputs of translational research in oncology by consensus.
Specifically, we wanted to explore the scope and issues of translational research relevant to evaluation and the views of researchers on the evaluation of oncological translational research, and to select indicators measuring the outcomes and outputs of translational research in oncology by consensus.
Our preparation may prove a useful, novel and, importantly, translational electrophysiological model for evaluation of candidate anti-migraine compounds in the laboratory.
The present study used a mix of qualitative and quantitative methods to investigate the views of researchers on the evaluation of translational cancer research outcomes.
Alterations in the serum levels of the miR371 3 and miR-302/367 MiRNAs also show promise as a diagnostic and follow-up tool for TGCT patients [ 38], highlighting the potential translational impact of molecular evaluation.
A molecule is not a drug, neither is active one and "druggability" is a key factor in the systematic process from molecule to drug, while translational research with "risk evaluation" is the decisive element.
From a clinical point of view, our results could have an immediate translational relevance since the evaluation of stathmin and p53 expression could be used to identify EOC patients with poor prognosis who may benefit from more aggressive/alternative therapies acting in M phase.
However, this can also be explained by limitations of the various experimental high through put approaches and at the moment it is difficult to evaluate the contribution of true translational regulation and/or poor protein evaluation along with its quantification.
