Sentence examples for translational defect from inspiring English sources

Kirino, Y. et al. Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease.

This moderately reduced replication capacity cannot be attributed to a translational defect of the chimeric 5'NTR (Fig. 2).

Deletion of the PERK gene restores the translational defect and rescues the neurodegenerative phenotype [ 60, 65].

This suggested that the erythroid-specific translational defect exhibited by rps19- and rpl11-deficient zebrafish was not attributed to the tissue-specific expression of rps19 and rpl11.

These findings suggest that the erythroid protein production defect we observed in both rps19 mutants and rpl11 mutants was not simply contributed by general translational defect.

To exclude the possibility that general protein translational defect led to erythroid protein production deficit, we examined the translational rates in both models.

First, like eif3h mutants, rpl24b mutants under-translate the AtbZip11 mRNA, and the detailed spectrum of translational defects in rpl24b is remarkably similar to that of eif3h.

For this study, we sought to identify the translational defects in two new types of mutants that affect the translation apparatus.

Our study further suggests that some of the developmental defects in the zebrafish models for CdLS are caused by translational defects, because treatment with l-leucine and α-KIC can partially rescue translation and development.

Regarding NHP2 synthetic lethality, numerous snoRNAs deletions have been described as yielding defects in ribosome biogenesis defects causing translational defects [12], and the rps15-1 mutaffectsffectranslationalnaccuracyacy (GS & FG, unpublished).

There are no reports of mRNA-specific translational defects for any pab mutant.