Sentence examples for translation the effect of from inspiring English sources

They suggest that if transcription and translation were coupled, and because splicing is expected to have been slower than translation, the effect of insertion would have been ribosome readthrough into introns, resulting in production of aberrant proteins.

Before clinical translation, the effects of SERCA2a were evaluated in a Yorkshire-Landrace swine model of volume-overload HF.

The modelers chose this mRNA length because it allows certain key properties of translation — the effects of the physical size of the ribosome on the accessibility of the start codon and the potential for "queuing effect" along the string — to be modeled.

Since there is no specific inhibitor for HIF-1 α translation, we determined the effect of IL-1 β on HIF-1 α translation by studying the influence of IL-1 β on the global regulator of eukaryotic translation phosphoinositide 3-kinase (PI3K /AKT/mTOR pathway, which also regulates the translation of HIF-1 α.

In both Gladiolus and Arabidopsis the 5′UTR-intron stimulated translation efficiency supporting the effect of the 5′UTR-intron at the post-transcriptional level.

Existing models of translation, already span a broad spectrum from the single ODE model to the detailed computational model of translation incorporating the effects of many factors [ 28].

Translation of the effects of inhaled nicotine on the CNS into clinical settings could provide important health considerations.

Gladstone et al. report that Bouvardin, a compound previously identified in a Drosophila screen as an inhibitor of protein translation, enhances the effects of radiation and the anti-cancer agent taxol in several preclinical models.

Since Prep1 can bind both some mRNAs and the 4EHP translation inhibitor, we studied the effect of the Prep1-4EHP conplex on Hoxb4 mRNA translation in vitro using a rabbit reticulocytes lysate translation system.

Another factor which could contribute to variability in measurement of disease progression in these multinational clinical trials is language differences; although a centralized translation service was used to minimize the effect of translation on outcomes, this still does not guarantee equivalence among cultural groups or regions.

The total amount of mRNA could also decline in the mutant owing to reduced transcription or increased mRNA turnover accompanying diminished translation, which would offset the effect of decreased polysome abundance on the calculated translational efficiencies.