Sentence examples for translation suppression from inspiring English sources

Thank you for sending your work entitled "mRNAs with efficiently translated uORFs resist stress-induced translation suppression inflicted by eIF2 phosphorylation" for consideration at eLife.

Similar to PPP1R15A, it encodes a subunit of the phosphatase that dephosphorylates eIF2, thus providing feedback preventing complete translation suppression and also enabling recovery from the stress-induced translational arrest (He et al., 1997; Jousse et al., 2003).

To evaluate the role of mRNA depletion and translation suppression in EV71-induced host shutoff, we carried out several analyses.

We therefore determined the effect of CUGBP2 knockdown on curcumin-mediated translation suppression of COX-2 and VEGF mRNA.

It seems that miRNAs do not have any catalytic activity but rather act as sequence-specific guides for associated protein complexes which are responsible for translation suppression or degradation of mRNA [2].

Different genetic alterations of PTEN, including mutation, deletion, and translation suppression, could lead to aberrant EGFR pathway activation in GBM.

In this study, we deliberately designed siRNAs that simultaneously direct cleavage and translational suppression of HIV RNAs, or cleavage of the mRNA encoding the HIV coreceptor CCR5 and suppression of translation of HIV.

Upon activation, ERK phosphorylates a number of substrates including kinases and transcription factors that mediate entry and progression through the cell cycle, inhibition of differentiation, protein translation and suppression of apoptosis [16].

We have also analysed two different aspects of the fidelity of translation: nonsense suppression and aa-tRNA selection.

Previously, a number of studies have established a link between compromised chloroplast translation and suppression of var2 [ 31, 32, 34].

In a recent report by Triboulet [ 17], miR-17-5p washownwn to bind to PCAF 3'UTR to suppress translation, resulting in suppression of the PCAF gene at the posttranscriptional level in HeLa cells.