This research enables the translation of quantitative techniques to widespread clinical use for the benefit of the patient.
Large animal models play a crucial role in sports surgery of the knee, as they are critical for the exploration of new experimental strategies and the clinical translation of novel techniques.
Large animal models play a crucial role in orthopaedic sports surgery, as they are critical for the exploration of new experimental strategies and the clinical translation of novel techniques (Espregueira-Mendes & Karahan 2014).
The translation of such techniques to preclinical models holds tremendous potential for investigation of cancer biology and drug development.
Such skills are important for undergraduates in building a conceptual understanding of translation of laboratory techniques to changes in human biology due to disease.
Future efforts will include translation of the techniques into in vivo studies and evaluation of the methods for use with microbicide candidates that are believed to have minimal cytotoxic effects but may nonetheless alter the vaginal epithelium.
However, we believe that the implication can further be generalized to other network topologies, although a pure translation of the techniques that we are currently using is not possible.
Translation of these techniques to in vivo imaging modalities, such as the MDCT and HR-pQCT, are subject to technical limitations related to image quality, radiation dose considerations, and subject motion.
The translation of this technique to the clinical environment, however, requires robust and systematic optimization of the acoustic parameters needed to achieve a desired therapeutic effect.
The successful clinical translation of this technique as part of a therapy requires the ability to measure extracellular matrix (ECM) production of engineered tissues in vitro, in order to ensure quality control and improve the likelihood of tissue survival upon implantation.
