Sentence examples for translation level of the from inspiring English sources

Currently, there are few approaches to precisely detect the expression level of the target protein, not to mention the technique for real-time monitoring of the translation level of the recombinant protein.

Maybe this was because of the 3-HPA accumulation during the early stage of fermentation inhibited the central carbon pathway at the post translation level of the cell growth, which could result in irreversible damage to cells in the fermentation broth and would cause an irreversible cessation of the fermentation process until the end of fermentation [[11],[14]].

miRNAs are capable of down-regulating both mRNA transcription and translation levels of the target gene [1].

Our data show that this downregulation is mainly derived from the low translation levels of the RP genes in the MT compared to the E stage, since similar levels of steady state mRNA are found in both stages.

The authors hypothesized that the augmented production of this protein was achieved either by an increase in the translation levels of the existing mRNA or by a slowing down of the turnover of the existing proteins [ 32].

Furthermore, while the translation levels of the TS family is significantly lower in the E stage when compared to the rest of the genes, in the MT stage the behavior is reversed explaining the high difference in TE between the stages (Additional file 10).

Cell lysates are treated with nuclease to degrade all mRNA not physically protected by ribosomes, and the ribosome-protected fragments are extracted, sequenced, and mapped back to the genome to show ribosome positions, revealing the overall translation level of each gene as well as the distribution of ribosomes along the mRNA.

Furthermore, we assessed the translation level of GDNF in lumbar spinal cords of the BCIP model (Fig. 4c).

The translation level of GluA1 and GluA2 subunits was significantly increased, but the surface expression level of GluA1 is reduced in the amygdala of fragile X mental retardation 1 (Fmr1) knock-out mice.

The common mechanism suggested by these genes is that the SL phenotype observed can be suppressed by increasing the levels of certain mRNA(s) as well as their transport from the nucleus (through the nuclear pore), perhaps causing an increase in the translation level of (a) target gene(s).

By changing the amount of rare codons inserted into ORF1, we sought to change the translation level of ORF1 and subsequently affect mCherry expression in ORF2.