Sentence examples for translation is compromised from inspiring English sources

This cap-independent mechanism of translation initiation regulates translation of specific eukaryotic mRNAs in response to stressful conditions in cells where cap-dependent translation is compromised [17].

We do not find that translation is compromised in eEF1A1 knockdown cells.

In situations where cap-dependent translation is compromised by cyto- or genotoxic stress, cap-independent protein translation, promoted by internal ribosome entry sites (IRES), is required to maintain expression of critical proteins [ 12, 13].

In other cases, control signals in the 5'-UTR provide continuous regulation of essential mRNAs by providing an alternative route for translation when cap-dependent translation is compromised (e.g., under stress conditions) [ 4].

Consistently, a number of apoptosis regulators including p53, Bcl-2, Apaf-1 and XIAP were reported to be generated from IRES-elements under conditions of stress, thought to maintain a functional apoptotic machinery when CAP-dependent translatisn is compromised (40).

Furthermore, CAP-dependent translation was compromised by inhibition of the PI3K/AKT pathway or mTOR using LY294002 or rapamycin, respectively (27).

However, under many cellular conditions (mitosis, apoptosis, cellular stresses of hypoxia and heat shock, and viral infection) when cap-dependent translation initiation is compromised, protein synthesis is mediated via an alternative initiation pathway, the internal ribosome entry site (IRES) dependent translation initiation [ 31].

And like all translation, language is compromised and propelled and made more wondrous by its unreliability, its shifting nuances, its shadows and half-suggestions, all the gaps where we might find ourselves.

The initiation of translation via cellular internal ribosome entry sites plays an important role in the stress response and certain physiological conditions in which canonical cap-dependent translation initiation is compromised.

LTM specificity is compromised.

The large representation of RP mRNAs and translation initiation factors that were down regulated in the protein biosynthesis category, support the idea that ribosome biogenesis and translation initiation were compromised in myo1Δ strains.