Sentence examples for translation interference from inspiring English sources

It has previously been shown that selection cassettes located within introns or regulatory regions, such as pgk-neo that we used here, can hinder expression of targeted genes via transcriptional and/or translation interference either by design ([38]; additional examples cited in [39]) or inadvertently [40], [41], [42], which sometimes proves to be serendipitous [42].

Second, genetic approaches are used to reduce or eliminate protein expression by targeting the gene coding for the protein of interest (genetic knock-out) or interfering with gene transcription or translation (RNA interference, antisense RNA).

They include the alteration of target RNA stability, the modulation (inhibition or activation) of translation, transcriptional interference and attenuation.

Given that the ribosome can synthesize oligopeptides without elongations factors and GTP, albeit at a very slow pace [ 109, 110], one may use such factor-free in vitro system to probe how the presence and absence of L9 as well as different copy numbers of L12 dimers regulate translation without interferences from other factors.

Intracellular delivery and endosomal escape of functional small interfering RNAs (siRNAs) remain major barriers limiting the clinical translation of RNA interference (RNAi -based theRNAi -based

NATs have been implicated in several processes such as RNA translation and transcriptional interference, where they play a pivotal role in cancer.

The packet-based memory access model (PDMA) has provided a scalable and flexible solution for distributed memory management, but suffers from complicated and costly on-chip network protocol translation and massive interferences among packets, which leads to unpredictable performance.

Our aim was to design a recombinant plasmid useful for detecting PSCs in human genes and resistant to bacterial translation re-initiation interferences.

To explain the effect of microRNA interference with translation initiation factors, a non-linear version of the translation model was proposed [ 41] which explicitly takes into account recycling of initiation factors (eIF4F) and ribosomal subunits (40S and 60S).

RNA interference: Blocking translation If a micro-RNA binds to a matching region on a strand of messenger RNA, it will block the ribosome from reading the strand and disrupt protein production.

Depending on the surroundings, this can affect transcription, translation or even RNA interference (RNAi) efficacy.