Sentence examples for translation divergence from inspiring English sources
We also found a significant correlation between the GC difference and the translation divergence (supplementary fig. S4, Supplementary Material online) for orthologous genes.
We performed cellular mRNA and RFP sequencing to investigate the transcription and translation divergence between cocultured parental strains of Scer and Sbay, as well as their hybrid (fig. 1 A and B).
With more stringent criteria, the numbers of differentially transcribed and translated genes were both reduced, but the general conclusion that more genes show transcription than translation divergence between two species was still similar (supplementary fig. S1, Supplementary Material online).
Divergence can alter the translation rate, degradation rate, subcellular location, and function of the encoded proteins.
Therefore, divergence of translation efficiency could reveal orthologous gene functional differentiation across species [ 15].
Buffering effect of translation on gene transcription divergence was also revealed in another study (Khan et al. 2013), which demonstrated more conserved evolution at the protein level than the gene transcript level, indicating that gene transcription divergence could overestimate the speciation difference in gene regulation.
Amino acid divergence between translations of C. virginica annotated reftigs and C. gigas coding sequence averaged 23.2 % with an average dN/dS ratio of 0.074, suggesting purifying selection on protein sequences.
The divergence of mitochondrial translation initiation relative to that of bacteria may be a result of neutral drift fuelled by the high mutation rate of the mitochondrial genome [96].
Comparison of binding profiles was performed using a novel algorithm that determines the similarity between TF motifs using the minimum Kullback Leibler divergence between all translations and reverse complementations of the multinomial distributions defined by the motifs.
For this purpose, we developed a computational method that allows determination of similarity between TF motifs using the minimum Kullback Leibler divergence between all translations and reverse complementations of the multinomial distributions defined by the motifs.
