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As for the Chinese version of WHOQOL-OLD, we followed the WHOQOL method in the process of translation and response scales development.
The top three categories for each of these comparisons were "cell cycle," "tRNA aminoacylation for protein translation," and "response to bacterium".
Similar(58)
Main Outcome Measures: Weight symmetry scores, latencies of each leg's active response to the support surface translations, and response strength scores of each leg to the platform translations.
We found that pathways in our results, such as "type I IFN-mediated signaling pathway," apoptotic processes, "immune response," reduction in translation processes and "response to virus".
For example, the majority of constitutively expressed gene products have GO term annotations that place their putative functional role in fundamentally important 'house-keeping' processes such as translation (GO 0006412) and response to heat and stress (GO 0009408 and GO 0006950) (Additional file 10).
These proteins carry out functions as diverse as tRNA synthesis, transport of amino acids, protein translation and stress response.
However, as these miRNAs under-expressed in MS were known to increase transcription of genes involved with translation and immune response pathways, we expected they may also contribute to the pattern of gene dysregulation seen in MS whole blood mRNA.
However, GSEA, Onto-Express, Pathway-Express and MetaCore analyses identified genes that control cell cycle, DNA replication and repair, transcription and translation, and immune response as the most perturbed in NF1-haploinsufficient conditions in both human and mouse.
First, molecular microbiological information allows relevant trait effects to be identified, as in the example of rpsL mutations that affect both translation and stress response induction (Paulander et al. 2009).
Thus, a predictive understanding of the effects of resistance alleles on bacterial growth parameters may be gained by quantifying their effects on specific processes, in this case translation and stress response induction, in different conditions.
Gene Ontology (GO) classification using the DAVID algorithm indicated that genistein and BMP6 both affect 48 fundamental cellular processes (Supporting Table 3), including translation and stress response, whereas KEGG pathway analysis demonstrated that both genistein and BMP6 increase transcript levels of ribosomal proteins (Supporting Table 4).
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