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While our current understanding is that contraction-sensitive allosteric factors (e.g., Ca2+, AMP, NAD+, and acetyl-CoA) initiate signaling changes, how the muscle translates changes in these factors into the appropriate adaptive response remains poorly understood.
The close lateral linkage of water conducting xylem with phloem translates changes in tree water status directly to shrinking and swelling of non-lignified tissues in the bark and phloem (Molz and Klepper 1973; Zweifel and Häsler 2001).
Due to this particular characteristic, SIRT1 has been proposed to act as an intracellular NAD+ sensor that translates changes of the metabolic/redox state of the cell into adaptive transcriptional responses [ 12].
LapD is a c-di-GMP receptor that translates changes in the concentration of this cytosolic second messenger into cell-surface events via an inside-out signaling mechanism that ultimately controls cell adhesion (Newell et al., 2009).
TGF is an intrarenal regulatory system that operates at the level of the juxtaglomerular apparatus, and that translates changes in NaCl concentration at a distal tubular site, probably the macula densa, into inverse changes of glomerular capillary pressure and nephron filtration rate.
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Whatever else it does or doesn't do, design helps us to translate changes in other fields — scientific, political or whatever — into things that may be useful or enjoyable, ideally both.
Change is most likely when important officials are able to translate changes in such way that it suits with a culture's core values.
To meaningfully interpret trials using surrogate outcomes, one must translate changes in the surrogate outcome to changes in the clinical outcome.
Therefore, the synaptic vesicle-associated synapsin phosphoproteins act at the intersection of cAMP and calcium-dependent cascades making them optimal candidates to translate changes in cAMP levels into modulation of vesicle recycling.
The long-term cost-effectiveness of U@Uni was estimated using an economic model developed to translate changes in health behaviours into long-term life years and QALYs.
RNA polymerase plus the ribosomes that together translate changes in the concentration of metabolites to changes in gene expression, or direct metabolic regulation of the activity of an enzyme correspond to such control actions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com