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The conceptual framework and corresponding items were designed in English, but translated into the study languages prior to each round of cognitive debriefings.
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For those compounds translated into the clinic, PK studies should then be performed to confirm that the exposure-time relationship observed in preclinical models is also observed in the clinic.
Questionnaires were translated and back translated into the major languages of the study participants (Afrikaans, Tswana, Xhosa and Zulu).
Questionnaires were translated into the six languages in the study, back translated to English by someone unaware of the original English version, and compared to the original version to ensure meaning was retained.
The CHEXI was translated into the different languages used in the study.
The questionnaire used was translated into the commonly spoken languages in the study area.
The questionnaire was translated into the major language spoken in the study area (Zulu) and verified by a second translator.
Then it was translated into the Amharic, local language of the study area by linguistic professionals.
It was later translated into the Amharic, local language of the study area.
Translated into the context of the current study, parents whose children exhibit some conduct problems might be less willing to participants in studies such as the current one.
Each survey was pilot tested, translated into the national language of the respective study countries, uploaded into the open source online software package LimeSurvey, and sent by e-mail to HPs in the six areas, who were identified by board membership of clinical associations, professional networks, ECDC focal points, scientific literature and other means.
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