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Therefore, in arousal regulators, cotransmitters may translate distinct features of OHN activity into parallel, nonredundant control signals for downstream effectors.
Future work will focus on identifying cellular mechanisms that translate distinct changes in Kv3.3 function into differential effects on neuronal development.
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These findings suggested the possibility that increased expression of specific ribosomal proteins in unique tissues might lead to the heterogeneous ribosomes in the distinguished cell tissues by specificities in translating distinct classes of mRNAs.
We were particularly interested in whether the use of these distinct heterodimer complexes would translate to distinct, receptor complex-specific, responses to TLR2 ligands.
Based on these observations we hypothesized that the distinct peripheral insulin profiles obtained with the abovementioned insulin preparations could translate into distinct hepatic exposures to insulin and in this way affect the liver production of IGF-I and IGFBPs differently.
However, the distinct features of mouse Brca1 Δ/Δ ;p53 Δ/Δ and Brca2 Δ/Δ ;p53 Δ/Δ tumors did not translate to distinct features of human BRCA1 and BRCA2 mutated tumors and vice versa.
Also, a pressing question is whether the different attitudes toward the role of the state among those with family abroad and in contact with it that we have found in this study translate into distinct political behaviors.
Whether these apparent disparities reflect biological divergence sufficient to translate into distinct ecological regimes (or animal reservoirs) bears investigation.
A direct comparison of gene expression profiles in control, acute and chronic TNF-stimulated T cells suggests that differences in TNF-R signalling translate to distinct gene fingerprints.
Our next goal was to develop computational models to help us understand how differences among substrates translate into distinct times of degradation onset.
Using gene expression profiling, it could be shown that these differences in signaling magnitude and duration translate into distinct responses at the transcriptome level.
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