The data presented here suggest that, while alternative splicing may produce novel translated combinations of the primary amino acid sequence, there is also a large number of transcripts produced by the AA, AD, and RI classes having either frameshifts or PTCs that may have a role in post-transcriptional regulation.
By expressing weather conditions in terms of the equivalent temperature if dew point temperature were 14°C, Steadman translated combinations of air moisture and temperature [and other factors such as wind speed and sun radiation, in his original papers (Steadman 1979a, 1979b)] into a single scale, measured in the same units as air temperature.
The developers note that it tends to do better with soups than complex plated meals (I wonder why), but it demonstrates a particularly complex set of AI capabilities: the ability to parse the written recipe, translate the combination of the ingredients and the cooking instructions into an expected output, and combine the multiple outputs into a generated image.
A derivative of ABT-737 as well as proapoptotic TRAIL receptor agonists are currently under evaluation in early clinical trials, suggesting that it is in principle feasible to translate this combination approach of ABT-737 and TRAIL into clinical testing.
Our data confirmed the preclinical advantage of the association between an antiangiogenic drug and metronomic chemotherapy, as also recently shown by Ma and Waxman (2008), and may improve the possibility to translate a combination therapy based on metronomic irinotecan and VEGFR tyrosine kinase inhibitors into the clinics to reduce the toxicity and enhance the antitumour effects.
FOR Molly Picon, a star of Yiddish theater, it all came down to chutzpah -- that tough-to-translate combination of nerve, audacity, grit and attitude.
The commission uses a programme called Systran, which it has adapted to translate various combinations of English, French, German, Italian, Dutch, Spanish, Portuguese and Greek.Acceptance of English, French and German as the commission's working languages obviates the need to translate every scrap of paper into all 11 official languages.
This illustrates the utility of integrating functional genomics screens with bioinformatics to identify and translate drug combinations into clinical study.
In agreement with other literature data, our in vitro and in vivo results point toward additive and synergistic anticancer effects between AZD1152 and conventional chemotherapy, and our hope lies in the possibility to translate such combinations into the clinic.
With the aim of translating the combination treatment regimen for clinical use, we studied the effect of combined treatment in patient-derived glioma cells.
The program translates sound combinations into symbols-- AAABBB" or "ABACC", for example--that enable both the computer and human analysymbols-- AAABBBsymbols-- AAABBBs.
