Each unwinding step consists of two or three hidden steps, suggesting a coupling ratio of 1 1 between base pairs unwound and dNTP hydrolyzed, and indicating accumulation of elastic energy, before transitioning to a subsequent phase.
The concept that nucleic acid motors can have a hierarchy of different-sized steps or can accumulate elastic energy before transitioning to a subsequent phase (Ali and Lohman, 1997, Bianco and Kowalczykowski, 2000, Kapanidis et al., 2006, Lucius et al., 2002, Moffitt et al., 2009, Myong et al., 2007, Revyakin et al., 2006, Schwartz et al., 2009) is further supported by our data.
Our data suggest a coupling ratio of 1 1 between base pairs unwound and dTTP hydrolysis, and they further support the concept that nucleic acid motors can have a hierarchy of different-sized steps or can accumulate elastic energy before transitioning to a subsequent phase.
Nobody had transitioned to the next phase.
I successfully transitioned to the R00 (Independent investigator) phase of my NIH grant in 2013.
Delaying the phase of the subway that will run through Beverly Hills could have a "domino effect" on the subsequent phase of the project, to West L.A. and Westwood, Wu wrote.
The transitions from the Match state were set with probabilities.9 to enter the DeletionOut state,.095 to transition to the subsequent Match state,.0025 to transition to the Insertion state, and.0025 to transition to the subsequent Deletion state.
Ms. Peters said the transportation authority would have to apply to her agency for financing of the subsequent phases.
A selection of important publications on SABR for lung metastases are displayed in Table 2. > The University of Colorado carried out a phase I clinical trial to determine the MTD for SABR of lung metastases; there was to be a seamless transition to a subsequent phase II trial.
The K+ cations controlled the morphology of β-MnO2 by affecting the formation of α-K0.5Mn4O8 α-K0.5Mn4O8e phase and the subsequent phase transintermediate
Consequently, the subsequent phase adjustment fails to correct phase errors.
