As with the remifentanil treatment group, in the patients who continued to require analgesia and sedation beyond day 3, propofol was discontinued and replaced with midazolam in accordance with local transitioning protocols.
(c) Asynchronous transition protocol.
A transition protocol was developed and implemented.
To design a suitable transition protocol, a survey of teenage patients with cystic fibrosis was carried out and the process was discussed with the relevant clinicians.
And does the reduction in knee-joint loading warrant a lengthy and strict adherence to a barefoot running transition protocol?
A copy of any transition protocol was requested.
22 24 Clinical protocols and guidelines (eg, a transition protocol for the transition from paediatric to adult care) for optimal chronic care delivery are needed and should be integrated into daily practice to provide decision support for professionals.
With our transition protocol, hypoglycemic episodes occurred in approximately one quarter of patients on the first 3 days of subcutaneous therapy, a rate similar to that observed in other studies.
The few studies that have examined the course of blood glucose (BG) after interruption of intravenous insulin have documented inadequate control in the absence of a standardized transition protocol (9, 12).
Other reasons for discontinuation included need for a mood stabiliser (n=3; 2 in quetiapine group, 1 in placebo group), inability to tolerate the transition protocol (n=7; 4 in quetiapine group, 3 in placebo group), and unwillingness to attend the study assessments (n=1; in placebo group).
