Sentence examples for transitional compartment from inspiring English sources

In each patient, there was again a reduction in tetramer-binding B cells as the B cells matured from the transitional compartment to the naïve compartment (Figure 5).

Nevertheless, NZB dTg mice had an increased proportion of T2 (CD21intCD24hi) and follicular B cells (Fo, CD21intCD24int), which appeared to result from a shift towards a more mature phenotype within the transitional compartment (Table 1).

However, at the transitional B-cell stage this inhibition was reversed with enhanced selection of B cells into the transitional compartment.

Like GFP-VPS35, GFP-VPS35(D620N) localized predominantly to a sorting nexin-1 (SNX1) positive early-to-late transitional endosomal compartment.

Since the majority of membrane-associated GBF1 and ABD was located in pericentriolar Golgi and transitional ER compartments (which rarely traverse the evanescent plane in TIRF imaging), good contrast was achievable near the plasma membrane where the concentration of GBF1 and ABD was relatively low.

This reduction in the transitional B-cell compartment compared to the mature B-cell compartment (75%) might be due to overall reduced numbers of developing B cells in the obtained RDBC chimeras and to the accumulation of mature B-cells in the periphery of these mice and not to a defect in B cell development.

Within the preimmune/natural effector compartment, transitional, pre-naïve and naïve B cells were identified as cells lacking the expression of CD27 and further defined by the expression of CD38, CD5 and/or Ig isotypes [23].

Recently, a population of human regulatory B cells (Breg) residing within the transitional B-cell compartment expressing high levels of CD24 and CD38 has been described (22).

Emigration of immature B cells to the periphery and their acquisition of membrane-bound (m IgD antigen receptors indicates entry into the transitional B cell compartment.

The number of B cells belonging to the preimmune/natural effector compartment, including transitional, pre-naïve, naïve and MZ-like subsets, was significantly higher among HHV-8 positive subjects, with or without cKS, while was comparable to healthy controls in the antigen-experienced T-cell dependent compartment.

Interestingly, IL-10-producing regulatory B cells are enriched in both memory (CD27+) and transitional (CD38high) B cell compartment [ 135].