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The male germline transcriptome changes dramatically during the mitosis-to-meiosis transition to activate late spermatogenesis genes and to transiently suppress genes commonly expressed in somatic lineages and spermatogenesis progenitor cells, termed somatic/progenitor genes.
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Third, how are the regulators of the epithelial-mesenchymal transition able to activate this profound change in cell phenotype?
Stiff PAA hydrogels, mimicking the PDAC mechanical microenvironment, were shown to induce PSC phenotypic transition to an activated, higher matrix secreting state.
The space demonstrates mass transition by enabling individuals to activate the wall with their ID card and type a word that is on their mind based on a prompted part of speech to modify part of an existing sentence.
When the main module fails, the transition TACT is fired to activate the spare module, similarly to the cold redundancy.
The main inductor of this transition is TGFβ3 able to activate key EMT transcription factors like Lef1, Twist and Snail1.
First, we envision a new approach to catalysis utilizing transition metal-ligand pi-bonds to activate sigma-bonds towards addition reactions.
EDCs and EPCs respond to fibroblast growth factors (FGFs) in both embryogenesis and regeneration processes and undergo a number of cellular modifications11 that is required to activate the transition from epithelial to mesenchymal cells, such as cytoskeletal re-arrangement and expression of hyaluronan-mediated motility receptor, neccessaries to move in the damage site 12,13.
In this experiment, the transitions of M.HhaI from inactive to activate state were driven by applying RMSD restraints with a force constant of about 1 kcal/mol/Å to each heavy atom of the catalytic loop (residues Cys81 Leu100).
Wu, C. F. et al. Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis.
Before discussing the island/wire stability, it is interesting to estimate the Si content which is needed to activate the shape transition.
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CEO of Professional Science Editing for Scientists @ prosciediting.com