Sentence examples for transition phenotype in from inspiring English sources

Morphology and transcritpome analysis indicated that platelets induce an epithelial-to-mesenchymal transition phenotype in both cells lines, with a more exaggerated response in SK-OV-3 cells.

In previous studies, we found that GLI1 was aberrantly overexpressed in HCC and predisposed to poor prognosis after liver resection by inducing the epithelial mesenchymal transition phenotype in a SNAI1-dependent manner.

Again, the fus3 phase transition phenotypes in the presence of AgNO3 were similar to those seen in the fus3 ein2 double-mutant.

These results suggest that increased ethylene signaling does contribute to the advanced vegetative phase transition phenotype observed in fus3.

We cannot discount the possibility that retention of Rad23p and the G1/S transition phenotype result from subtle differences in ROS levels that are not detectable by our methods.

Previous work has provided initial characterization of IGF-IR-independence and has demonstrated the presence of an epithelial-mesenchymal transition (EMT) phenotype in these recurrent tumors [ 13].

Grassian et al. showed that high levels of the oncometabolite 2-HG, produced by mutant IDH1 enzyme, cause an epithelial-mesenchymal transition -like phenotype in IDH1 mutated cells by changing the EMT-related gene expression and cellular morphology [ 20].

Figure  1 shows that compared to control cells (mesenchymal and elongated, typical feature of EMT phenotypic cells), GN-25 showed reversal from EMT to Mesenchymal-to-Epithelial Transition (MET) phenotype in the SNAIL and Kras plus SNAIL transduced HMLE cell lines (epithelial round cells in higher dose treatments at 24 and 48 hrs).

MVA-NAO was less sensitive and detects a sharp transition in phenotype at around 60 70 μM tamoxifen.

The signals that regulate the process of chronic leukocyte recruitment into the diseased joint are poorly defined; however, it is probable that cells of the tissue stroma that have undergone a disease-specific transition in phenotype contribute to inflammation by the inappropriate production of proinflammatory cytokines and chemokines [ 1, 2].

In the healthy artery, contractile vascular smooth muscle cells (VSMCs) have an elongated shape and are highly aligned but transition to a synthetic phenotype in culture, while additionally becoming well spread and randomly organized.