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The single strand to helix transition of nucleic acid is usually driven by favorable enthalpic changes associated with an increased level of stacking and H-bonding interactions.
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Illustrative examples are discussed on applications of these thermodynamics models to computational design of proteins with improved function and stability, to charge-transfer equilibria, to structure transitions of nucleic acids and proteins, to protein ligand interactions, and to ion transport through lipid membranes.
In contrast, all the transitions between different forms of nucleic acids are, in principle, permitted and occur on some occasions.
But some of his ingredients, like the nucleotide building blocks of nucleic acids, are quite complex.
Principles of nucleic acid structure and function.
The accelerating pace of nucleic acid sequencing allows scientists to read any organism's complete genetic code.
His ambition was to discover the enzymes that made RNA and DNA, which are polymers, or chains of nucleic acids.
The AID/APOBEC family of nucleic acid mutators.
Synthesis of Nucleic Acids in Opalina ranarum Ehrbg.
Digital quantification of nucleic acid molecules and its efficacy.
Eschenmoser, A. Chemical etiology of nucleic acid structure.
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