Sentence examples for transition of effector from inspiring English sources
For example, deletion of Traf6, which encodes a signal regulating fatty acid oxidation, impairs the transition of effector T cells to memory cells [19].
Moreover, lineage transition of immune effector cells are observed in the different stages of the disease, with NK cells in the early stage and granulocyte leukocytes in the late stage.
We consequently evaluated the importance of AMPK for controlling the transition of metabolically active effector CD8 T lymphocytes to the metabolically quiescent catabolic memory T cells during the contraction phase of the immune response.
Considering these facts, Rolf et al. [ 53] investigated the role of AMPK during the contraction phase of immune response in regulating the transition of metabolically active effector CD8 T cells to the metabolically dormant catabolic memory T cells.
This treatment schedule focuses the effects of temsirolimus on the transition from effector CD8 T cells to memory cells.
Cell death through the mitochondrion involves an increase in mitochondrial permeability transition that results in the release of cytochrome c and downstream activation of effector caspases.
Over a period of days, T cells within tumors rapidly transitioned from a CD25hi/CD27hi to a CD25low/CD27low phenotype and displayed an increase in cytolytic capacity, indicative of effector maturation.
It is equally important to identify signals that allow effector T cells to return to a metabolically quiescent state as they make the transition from effector cells to memory T cells during the contraction phase of the immune response.
Temsirolimus was administered during the transition from effector phase to memory phase (days 8 32).
E2F transcription factors are the effectors of the G1/S transition of the cell cycle.
It is likely that this involves transition of the bacteria between replicating and nonreplicating states in response to environmental changes triggered by immune effector mechanisms and enclosure and escape from granulomatous lesions (Barry et al., 2009).
