Sentence examples for transition of cells from inspiring English sources

The transition of cells through the different stages from normal to cancerous can be thought of as an evolutionary process, in which there occurs a succession of genetic changes that undergo selection and determine the ultimate genotype (genetic constitution) of a tumour and its metastases.

The enhanced [3H]thymidine incorporation was inhibited and the transition of cells from static phase (G0/G1) to DNA synthesis (S) and mitotic phase (G2/M) was held back by iptakalim in a concentration-dependent manner.

Ding et al. [39] hypothesized the underlying protective biochemical mechanism, which may be due to inhibition of apoptosis by accelerating the transition of cells in the S phase to the G2 or M phase, as well as decreased levels of nitric oxide and caspase 3. Oxygen is required for cell survival.

Lack of Stella expression at the earlier stage could reflect a transition of cells committing to the germ lineage.

The transition of cells from G1 to the S phase of the cell cycle with the commitment to DNA synthesis is regulated by multiple factors [34], [35].

Dephosphorylation of cdc25A promotes the transition of cells from G1/S by removing the inhibitory phosphates on the cdk2/cyclinE complex [24], [25].

In order to capture the dynamic transition of cell-cell contact states, time-lapse microscopic analysis was conducted.

F-Box proteins participate in varied cellular processes such as signal transduction, development, regulation of transcription and transition of cell cycle.

In contrast, overexpression of HTm4 in U937 cells inhibits the G1-S transition of cell cycle through interaction with cyclin-dependent kinase-associated (CDK-associated) phosphatase-CDK2 (KAP-CDK2) complexes [15], [24].

For example, the Cdk inhibitors p21 and p27, cyclin E, and Rb regulate the transition of cell cycle from G1 to S phases, and Bub1, BubR1, Scc1/Rad 21, CENP-C, and INCENP are involved in the M phase progression [48] [50].

ERK1/2 activation leads to the phosphorylation of the protein phosphatase CDC25c during the G2/M transition of cell cycle progression [ 26].