The kymographs for Dll1 and Notch1 protein also show a smooth transition of the dynamic expression domain and, strikingly, depict pulses of Dll1 (and of Notch1, albeit to a lesser extent) protein expression levels in the caudal PSM (Fig. 6E,G).
In order to reduce the number of concurrent transitions, a dynamic MRM method was employed whereby specific transitions are only monitored at specific times, i.e., when the compound elutes.
In this regard we suggest a new role of ACP in HA formation, with a continuous organic mineral transition assisted by a dynamic pool of ACP.
Interestingly, a second population of trajectories (34%, n = 31/91) reach the high-FRET conformation but then transition irreversibly into a dynamic ensemble of states characterised by rapid FRET fluctuations from ~ 0.4 to ~ 0.9 FRET (Fig. 4b, bottom left).
The reality is that our power sector is in the midst of a dynamic transition and we may reach the Clean Power Plan goals even without the regulation in place.
As the city's diverse people struggled over the terms of the transition, they built the foundations of a dynamic, contentious hybrid metropolis.
The initiation of development upon fertilization, whereby a quiescent oocyte transitions into a dynamic embryo capable of differentiating into multiple cell types, is marked by the relocalization or degradation of a number of maternal proteins.
ArhGAP44 expression increases as the neuronal network is established and the frequency of exploratory filopodia formation is diminished, suggesting that ArhGAP44 may facilitate the transition of neurons from a dynamic exploratory mode to a mature more static state, a hallmark of nervous system development.
Thus, considering that ArhGAP44 expression increases with time, this suggests that ArhGAP44 may facilitate the transition of neurons from a dynamic exploratory mode to a mature more static state.
Here we report the direct detection of a dynamic equilibrium conformational transition in nucleosomes that greatly increases the distance between the end of the nucleosomal DNA and the histone core.
