Sentence examples for transition in tumor from inspiring English sources

A major transition in tumor progression seems to be loss of dependency of stromal interaction for proliferation.

Nuclear change shape also takes place during the epithelia-to-mesenchyme transition in tumor cells, and may contribute to metastasis (Thiery et al., 2009; Yao et al., 2011).

In this case, transitions in tumor markers (SLX and pro-GRP) appeared to occur in parallel with histological transformation.

These alterations are essentially stable through additional transitions in tumor cell phenotype and are evident in metastatic cells.

Such insights hold promise for increasing our understanding of tumors as self-organizing systems and, the possible existence of phase transitions in tumor growth kinetics, which, in turn, may have significant impacts both on cancer research and on clinical practice.

Such insights hold promise for increasing our understanding of tumors as self-organizing systems and, the possible existence of phase transitions in tumor growth kinetics, which, in turn, may have a significant impact both on cancer research and on clinical practice.

HGF-dependent Met activation plays an important role in stimulating epithelial-mesenchymal transition (EMT) in tumor cells, resulting in increased tumor cell proliferation, survival, motility, angiogenesis, invasion, and metastasis.

Firstly, since CD146 has also been identified as a novel molecule for inducing epithelial-mesenchymal transition (EMT) in tumor progression (Imbert et al., 2012; Liu et al., 2012; Zeng et al., 2012), not only does the absence or inhibition of CD146 function block tumor growth and angiogenesis; it is also likely to suppress tumor metastasis.

Moreover, TGF- β is also a well-known factor in immunosuppression, fibrosis, and the epithelial-mesenchymal transition (EMT) in tumor cells [ 47– 47].

Since chemoresistance is often associated with increased cell motility and invasiveness, it has been suggested that v-Src controls these activities by inducing the epithelial-to-mesenchymal transition (EMT) in tumor cells [ 8].

Based on its role in mesodermal development during mammalian embryogenesis [ 8, 9], TWIST1 is proposed to induce an embryonic event termed epithelial-mesenchymal transition (EMT) in tumor cells to promote the expression of mesenchymal junction proteins in epithelial cells and reduce intercellular junctions in the meantime [ 2, 10, 11].