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ET-1 and ETAR are overexpressed in ovarian cancer, driving epithelial-to-mesenchymal transition by stimulating tumour cell proliferation, invasive propensity (migration and adhesion), tumour cell escape from apoptosis and angiogenesis through multiple signalling pathways [ 120– 120].
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We presumed that the possible mechanism of FoxM1 in acceleration of G2/M phase transition could be by stimulating the cell cycle regulators other than cyclin D1.
Far from hurting our economy, such a policy would improve our economy by stimulating the transition to renewables and putting money in the average person's pocket.
Reprogramming is the activation of a pre-existing gene expression program caused by stimulating a transition into the attractor that encodes such a program.
The framework is not meant to be prescriptive nor predictive, rather it is meant to promote a deeper understanding of healthcare system transitions for optimizing patient-centeredness, by stimulating further investigations and discussions.
In the meanwhile, however, we believe that sharing the current proposition can promote deeper understanding of healthcare system transitions and optimization of patient-centeredness by stimulating investigative studies and discussions.
Therefore, we examined the phosphoinositide 3-kinase (PI3K) pathway, which is known to be involved in proliferation and growth of ES cells by stimulating the G1-S phase transition, and its inhibition induces apoptosis in ES cells [17].
All work by stimulating acetylcholine levels in the brain.
Bioorthogonal chemical imaging of metabolic changes during epithelial mesenchymal transition of cancer cells by stimulated Raman scattering microscopy.
Furthermore, mesenchymal-to-epithelial transition (EMT) stimulated by TGF-β and its interplay with AR signaling is important for prostate cancer cell migration [ 34, 35].
Altered proliferation, invasion, and epithelial-mesenchymal transition (EMT) stimulated by TGF-β in control and β3 integrin manipulated MECs was determined.
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