Sentence examples for transition by activating from inspiring English sources
The transcriptional activator E2F-1 is an important cell-cycle regulator, stimulating the G1/S-phase transition by activating the transcription of other cell-cycle genes [ 8].
In addition, the data show that miR171 over-expression alters the vegetative to reproductive phase transition by activating the miR156 pathway and repressing the expression of the TRD (THIRD OUTER GLUME) and HvPLA1 (Plastochron1) genes.
As a G1 cyclin, Cln3 triggers the Start transition by activating a downstream positive feedback loop composed of the repressor Whi5, the transcription factor SBF/MBF and the cyclin Cln1/2 (Skotheim et al., 2008; Charvin et al., 2010).
Previous work showed that Cut12 plays a role in promoting G2/M transition by activating polo kinase Plo1 upon mitotic entry (Bridge et al, 1998; MacIver et al, 2003; Petersen and Hagan, 2005).
Based on our results, we provide a model illustrating the specific role played by JC15 in conjunction with mtHsp70 to promote membrane pore transition by activating MPTP complex through CypD.
B[a]P exposure in human embryo lung fibroblasts accelerates the G1-S transition by activating MAPK and inducing cyclin D. Treatment with antisense cyclin D1 or antisense CDK4 completely inhibited B[a]P-induced cell cycle progression at the G1-S checkpoint [ 27].
It is involved in the G2-M transition in eukaryotes by activating CDC2 kinase and its inhibition induces cell cycle arrest [ 9, 22, 23].
It has been reported that p21WAF1/CIP1 can regulate the G1/S transition of cell cycle by activating CDKs and cyclin complexes, so the expression of cyclins might not be affected.
Plk1 also regulates centrosome assembly and separation, and controls the onset of G2/M transition in the cell cycle by activating cdc25c [ 62].
Previous studies in several model organisms revealed an sRNA class transition from piRNAs/siRNAs to miRNAs, and the transition is essential for the MZT by activating zygotic genome and clearing maternal RNAs [ 11- 18] 18].
For example, miR-106b can promote HCC cell migration and invasion by activating epithelial-mesenchymal transition (EMT) process (Yau et al., 2013).
