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Importantly, our results reveal how the presence of hydrogen dramatically influences the nature of the sp → sp2 transition, a key step in the nucleation of both graphene and carbon nanotubes.
It has been shown that oxidative metabolism of ethanol causes mitochondrial failure by activating mitochondrial permeability transition, a key event in regulating cell death [ 200].
Epithelial mesenchymal transition, a key developmental programme that is often activated during cancer metastasis and can be induced by ectopic expression of Snail, Twist, or by exposing cells to the TGF- β1 (Andarawewa et al, 2007; Thiery et al, 2009; Vesuna et al, 2009), is directly linked with de novo generation of CSCs.
On the other hand, recent data obtained on the model of immortalized human mammary epithelial cells (both normal and transformed), have demonstrated an unexpected linkage between the epithelial mesenchymal transition, a key developmental program, and acquisition of stem cell properties (Mani et al. 2008).
Szczyrba et al (2011) showed that miR-375 targets SEC23a, a putative tumour suppressor, while MiR-141 is a member of the miR-200 family, which targets the ZEB family of transcription factors, which function to repress the epithelial-to-mesenchymal transition, a key step in cancer metastasis (Gonzales et al, 2011).
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Moreover, formant transitions, a key aspect in the perception of speech, are also only covered indirectly by the MFCCs [3].
In post-crisis transitions, a key strategy has been to quickly resume schooling as a way to help children deal with whatever trauma they have experienced and return some sense of normalcy to their lives.
DeMenocal has argued that this transition was a key event in human evolution: right around the time that it occurred, at least two types of hominids — one of which would eventually give rise to us — branched off from a single ancestral line.
Epithelial-mesenchymal transition plays a key role in tumor invasion by disrupting intercellular contacts and enhancing motility and migration of tumor cells to the surrounding tissues [39], [40].
Epithelial mesenchymal transition is a key mechanism operating in the normal development of multicellular organisms.
Epithelial mesenchymal transition is a key step in the regulation of cancer metastasis.
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