During epididymal transit, functional and structural modifications leading to full maturation enable male gametes to reach, recognize and fertilize the oocytes.
To delineate the pharmacological modification of GI transit time, we selected the drug, loperamide, administered 30 min after 99mTc-Ch-DTPA gavaging.
Costs incurred by a wheelchair user are not negligible; wheelchair types (transit, electric, narrow, prescriptive), house modification, annual servicing, replacement, and caregiver for self-propelled wheelchairs all contribute to costs of care but were not considered in our analysis.
The protein undergoes a variety of posttranslational modifications during its transit from the ER and Golgi to the late lysosomes before it is secreted [ 27].
This study describes the characteristics of canine spermatozoa collected from the caput, corpus and cauda epididymis with the aim of highlighting the modifications occurring during transit.
Concomitant with these functional changes, spermatozoa undergo structural modifications during epididymal transit such as migration of the cytoplasmic droplet and acrosomal reshaping in order to achieve the normal morphology of mature spermatozoa [ 4].
SPCA1 is important for establishing a store of Ca2+ ions in the Golgi apparatus, which is required by Ca2+-dependent enzymes essential for post-translational modification of proteins in transit through the secretory pathway [ 15].
The current study determines chloroplast stromal protein abundance and N-terminal modifications, re-evaluates chloroplast transit peptides and cleavage sites, and provides a comprehensive catalogue and annotation of the chloroplast proteome, encompassing existing literature.
Pathways leading to pectin biosynthesis and modification altered on epidermal cells transiting to a TC fate (Additional file 13).
Only later did Toc-Tic-based translocation machinery evolve and, because this new pathway was more efficient, selection favored modifications of signal peptides into transit peptides in hundreds of nuclear-encoded, plastid-targeted proteins.
