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A stem cell, on the other hand, can divide to produce one stem cell and one progenitor or transit cell, which then proliferates into the tissue's mature, fully formed cells.
They divide by asymmetric cell division where one daughter remains a stem cell while the other daughter becomes a transit cell, which divides a defined number of times and differentiates.
Undifferentiated cells (the stem cell/early transit cell populations) are capable to proliferate [ 49].
At 6 and 12 h, PDTC reduced apoptosis among stem, presumed clonogenic and transit cell populations.
This suggests that the testicular architecture shifts towards the transit cell lineage in the species that produce many small sperm.
If the transit cell divisions correspond to a perfectly bifurcating tree, we would as a general rule expect F = 2 n t and S = 4 × 2 n t.
Similar(43)
Normal homeostasis of intestinal epithelium is maintained by an intricate cell replacement process in which terminally differentiated epithelial cells are continuously and rapidly replaced by replication and differentiation of epithelial cells (transit cells) located within the intestinal crypts.
Clonogenic and transit cells were reprieved (cell positions 6 13, P<0.001).
The germ cells are organized into long-lived basal stem cells (spermatogonia) and short-lived differentiating transit cells (spermatocytes and spermatids).
Oval cells are well known as amplifying transit cells and thereby have a high proliferating property under condition of hepatocyte damage in the liver (Hu et al, 2007).
This may result in an altered programming of ileal stem cells and transit cells that give rise to absorptive enterocytes over-expressing IBAT protein.
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