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The transient turnover of transduced cells minimally affected GALC activity, which was widespread and rapidly achieved in Twi mice upon neonatal injection of the therapeutic vector.
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The suggested increase in osteoclast activity in our data in spite of the improvement in vitamin D status and corresponding PTH suppression is surprising, but may represent a transient high turnover state with increased bone turnover as a result of increased bone formation.
The teenager was once firmly defined by age – classically, 15-24 – as well as the favoured transient, quick turnover products aimed at youth.
The coach said he used words like "transient" and "high turnover profession" in his welcome-back address this month to a team that had just jettisoned its career leading scorer.
Other difficulties street newspapers face include high turnover of "transient" or unreliable staff, lack of adequate funding, lack of journalistic freedom for papers that are funded by local government, and, among some demographics, lack of interest in homeless issues.
After confirming that there was a turnover of transient starch under the specific light conditions used, gene expression at different times of the day was analysed by microarray.
No increase was seen after a six-week exercise program indicating that any effect of individualized supervised exercise on cartilage turnover is transient.
We found that lipid and peptide inflammatory mediators and MMP activity show an early rise within 8 hours of induction of inflammation, with concomitant transient increases in aggrecan turnover markers within the first 24 hours.
LPS injection resulted in a swift and transient response of aggrecan turnover markers, both CS846 epitope and GAG release rising within 8 hours of LPS injection and returning to baseline after 1 week.
By monitoring transient kinetics under multiple-turnover conditions, one can often obtain kinetic information not available during steady-state measurements.
Wal-Mart attracts a transient work force, with frequent turnover making it difficult to train people over time.
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