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We show that the nature of transient linkage between the hemoproteins and the redox partners is most likely brought about electrostatically, although productive interaction between cytochrome b5 and CYP51 is governed by the membrane-insertable hydrophobic region in the cytochrome b5 which in turn determines the correct spatial orientation of the core.
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Previously, we have reported potential transient linkages between TCR clusters and cortical actin flow that collectively give rise to a frictional drag force to drive TCR cluster movement.
Information in nervous systems is often carried by neural ensembles — groups of neurons in transient functional linkage — and written in a code that involves the spatial locations of active neurons or synapses and the times at which activity occurs.
Transient Y linkage occurs in D. americana due to males with the X-4 fusion transmitting an intact unfused 4th chromosome to their sons.
In contrast, excessive polymorphism is accruing in association with transient Y linkage, and furthermore, hitchhiking with sexually antagonistic alleles is potentially responsible.
Transient parallel linkage of TIMAP and farnesyl transferase to RACK1 could ensure prenylation and transport of TIMAP to the plasma membrane where it may attend in maintaining the endothelial barrier as a phosphatase regulator.
HECT domain E3 ligases form transient thioester linkages with ubiquitin to a C-terminus active-site cysteine residue and transfer the ubiquitin moiety to the substrate bound to the N-terminus.
Next, the electrical spreading between adjacent cells was determined by assessing the coordination of spontaneous Ca2+ transients in monolayer NRVMs, because a direct linkage between GJs and coordinate Ca2+ transients have been identified [ 28, 29].
Our CLASPI approach overcame this difficulty by applying photo-cross-linking chemistry to convert weak and transient enzyme PTM interactions into irreversible covalent linkages, and enabled a systematic profiling of the 'erasers' of protein PTMs.
The current study was designed to delineate the role of peripheral P2Y1Rs in pain and to investigate potential linkages to mitogen-activated protein kinase (MAPK) in DRGs and Transient Receptor Potential Vanilloid 1 (TRPV1) expression in a rodent inflammatory pain model.
Starch synthase I catalyzes the elongation of glucans by the addition of glucose residues from ADP-glucose through the formation of α-1,4 linkages and is a major determinant for the synthesis of transient starch reserves in plants [ 105].
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