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Provided the endothelium-supporting function of perivascular ASCs, the transient fat mass reduction observed during the treatment could be because of the temporary indirect effect of D-WAT on adipose vasculature.
We have previously shown a lack of a dose response relationship between duration of PA and gain in fat mass [ 8, 23] and also a higher transient fat gain in boys [ 22].
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Notably, the mixture distribution has significant skill in capturing the transient behavior with fat tails of the high-dimensional non-Gaussian PDFs, and this facilitates the algorithms in accurately describing the intermittency and extreme events in complex turbulent systems.
Similarly to the observation obtained by comparing each time-point to day 0, the peak-intervening time-points are characterized by a more modest transcription response and may reflect resumptions of the local homeostasis resulting from the transient adaptation to excess dietary fat.
Protein starvation-induced autophagy in the larval fat body is transient, dropping after 12 to 24 h [ 22, 43] and LTR staining in the starved buffy mutant followed a similar timecourse (data not shown).
In the fat body, there was a transient increase in MsSCP-2 transcripts at the end and beginning of each instar (Fig. 2A, upper panel for fat body lanes B-C).
However, patients with disorders of lipid metabolism may be less able to rapidly clear fat from circulation, thereby resulting in transient triglyceride elevations.
Conversely, high-fat meals are usually followed by transient endothelial dysfunction in association with elevated triglyceride-rich lipoproteins [ 13].
This indicates a transient interaction of macrophages, fibroblasts, and the stroma of the mammary fat pad during the first stage of mammary fat pad humanization, which subsequently enhances future engraftment with human breast epithelial cells.
An acute bout of exercise also is marked by a transient increase in antioxidants that may protect the vascular endothelium after a high-fat meal [ 26].
Transient neutrophil infiltration into adipose tissue in obesity is also reported, which occurs 3 and 7 days upon high fat diet in epididymal but not subcutaneous fat and disappears on all subsequent times points (Elgazar-Carmon et al 2008).
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