Sentence examples for transient down from inspiring English sources

At the same time, transient down modulation of BSP and RECK in the osteogenic cells can specifically affect the organization of mature bone ECM.

During early chondrogenic differentiation in spheroid cultures ITM2A levels remained low in MSC and a transient down-regulation occurred in ASC correlating with successful chondrogenesis.

Assuming that HoxD-11 expression affects growth rates [17], we can hypothesize that transient down-regulation of HoxD-11 may relate to the partial reduction of these digits.

Based on our results we argue that the transient down-regulation of the Nanog expression in ES cells is a functional feature of these populations to regulate the susceptibility for differentiation signals.

A phenomenon particular to the alligator forelimb is a transient down-regulation of HoxD-11 expression in the posterior region of digits 4 and 5 at stage 16, as indicated by the black arrow.

To establish whether the TAP-2 deficiency displayed by OE19 is due to a transient down-regulation, OE19 was treated at several time points with different concentrations of IFN-γ: after 24 hours it was already possible to observe an up-regulation of TAP-2 in OE19, which notably increased after 48 hours (Fig. 5D).

GABPα and GABPβ displayed a similar expression pattern during differentiation of white and brown fat cells, with a transient down-regulation at days 1 and 2 (except for GABPα in Rb−/− cells) as well as a second down-regulation at the terminal stages of differentiation (days 6 and 8) (Fig. 5B).

A transient down-regulation of the dihydrokaempferol 4-reductase gene (ec 1.1.1.219) was recorded at 90 DAF (Additional file 5).

Gene network analyses suggest that changes in the activity of Fhl1 and PAC/RRPE-associated factors result in the transient down-regulation of genes involved in energetically costly programs of ribosomal biogenesis, protein synthesis, and rRNA transcription/processing.

However, the observation that neonatal exposure to both Aroclor 1254 and DES results in a similar phenotype by PND30 suggests that the transient down-regulation of Wnt7a triggers a permanent reprogramming of the developing reproductive tract.

Other RNA species (VIP, CD44, integrin-α-6) accumulated more slowly i.e. between 2 and 4 hrs following ts v-Src activation and did not show the transient down-regulation observed for the IL8/CEF-4 mRNA.