In addition, the temporal pattern of their activation is extremely important; a necessary immediate and transient consequence of hormone treatment is MAPK activation, whereas phosphatidylinositol-3 kinase activation must be sustained for at least 3 hours [ 47].
Although SUMO modification is transient, downstream consequences are long lasting and impact processes such as protein folding, subcellular localization, stability, transcriptional regulation, and protein activity (Geiss-Friedlander and Melchior, 2007), all of which are affected in HD (Zheng and Diamond, 2012).
In addition, it is conceivable that in some patients hyperlactatemia was a transient event (such as with seizures), with resolution without consequence.
Local genotypes are to a certain extent transient, being a consequence of past historical genetic patterns.
As a consequence, transient stabilization of vessels and improved oxygen delivery to hypoxic zones is achieved following VEGF neutralization.
Mixed HCV infection has previously been reported as being transient, as a consequence of a more effective immune response against one viral strain, or competition between variants with the fitter strain having an advantage over others.
The reason that its lifetime is not more transient as a consequence of this mutation may be explained by the crystal structure, which supports the proposal that a water forms a bridge between the shorter Asn103 side chain and the FeIV=O moiety through hydrogen bonding.
One may surmise that a transient adverse event in the ED setting is a benign or self-limited consequence of airway management [29].
An experiment on JET in 2013 designed to investigate the consequences of transient W edge melting on ITER, found significant deficits in the edge power loads expected on the basis of simple geometric arguments, throwing doubt on the understanding of edge loading at glancing field line angles.
Therefore, we sought to assess the consequences of transient overexpression of GADD34 on Gem-induced changes in polyribosomal sedimentation.
This stenosis, however, had only transient and moderate clinical consequences and did not preclude satisfactory breastfeeding, even with the tracheal cannula.
