TCR preferentially selected under Th2 conditions tended to use elongated CDR3α loops and when expressed in transgenics, skewed responses away from secretion of IFNγ, favoring Th2 cytokines.
OsKSL8 and OsKSL10 showed only a slight increase in expression than the control plants in transgenic plants in response to UV (Figure 4e-f).
To explore the functional role of miR132 in vivo, our lab generated a tetracycline response transgenic mouse strain, which bidirectionally drives the expression of miR132 and cyan fluorescent protein (CFP).
The Herpes Simplex Virus type 1 thymidine kinase (vTK) coding region is a component of a strategy for cell-type specific ablation in transgenic animals in response to the pro-drug ganciclovir (GCV) (reviewed in[18]).
This was despite a greater weight gain in the DDAH transgenic animals in response to the high fat diet (see discussion below).
The accumulation of a number of defense transcripts was similarly augmented in MBF1c transgenic Arabidopsis in response to heat stress [ 9].
As seen with PEV in other organisms, enhanced variegation was observed in these transgenic mice in response to HP1β over-expression [ 31].
An earlier study used multispectral imaging flow cytometry to count GFP puncta in plasmacytoid dendritic cells from LC3-GFP transgenic mice in response to VSV infection.
Furthermore, consistent with our microarray results carried out on partial resistance response, transgenic plants with lower cytokinin levels were found to be more tolerant to clubroot (Siemens et al. 2006).
The avoidance behaviour of Sstr2 transgenic animals in response to 25 μM SST-28 was strongly reduced after pre-exposure to 1 μM SST-28, whereas pre-exposure to 10 μM SST-28 could fully abolish avoidance of SST-28.
