Sentence examples for transgenic loss from inspiring English sources

Unlike the above five genes, the functions of the other genes were identified through transgenic loss of function studies.

Using transgenic mice, loss or activation of β-catenin has been studied in multiple tissues to elucidate its role in vivo.

The short-listed candidate genes can be further confirmed by transgenic approaches by loss or gain of function studies.

One tool for examining reactive astrocytes is by utilizing transgenic mice with loss of GFAP and vimentin (Pekny and Nilsson, 2005).

Furthermore, in a transgenic mouse model, loss of one or both bax allele(s) significantly accelerate c-Myc-dependent lyphomagenesis in a bax gene dosage-dependent manner (Eischen et al, 2001a).

To further study the function of SOFLs and their potential role in the cytokinin metabolism, we characterized both overexpression transgenic plants and loss-of-function mutants for the two Arabidopsis SOFLs, AtSOFL1 and AtSOFL2, which show higher similarity to each other than to SOB5 and SOFLs from other plant species.

To directly test their role in glucose-mediated neuroprotection, we crossed our mTDP-43 transgenics with the loss of function mutants daf-16(mu86) and hsf-1 sy441 hsf-1 sy441

We had previously shown discontinuous laminin-1 staining in the mammary glands of PR-A transgenics indicating a loss of BM integrity [ 6].

Although the influence of overexpression of GhWRKY15 in tobacco was explored, the mechanism underlying the function of GhWRKY15 should be elucidated in transgenic cotton and loss-of function data in cotton are particularly needed.

Using transgenic mice with loss-of-function and gain-of-function miR-21 alleles, Hatley and colleagues elucidated the role of miR-21 in NSCLC pathogenesis in vivo [ 37].

In the 1990s, several related transgenic approaches to induce loss of gene function in plants were developed.