Transfusion therapy of liver transplant patients remains a challenge.
Criteria for exchange blood transfusion therapy for leukocytosis with lymphocytosis are suggested.
However, transfusion therapy for SCD may incur special and distinctive adverse effects.
Transfusion therapy and phototherapy have greatly reduced the incidence of kernicterus.
Witt V, Fritsch G, Peters C, Matthes-Martin S, Ladenstein R, Gadner H. Resolution of early cytomegalovirus (CMV) infection after leukocyte transfusion therapy from a CMV seropositive donor.
The purpose of this study was to establish the true procedure-related complication rate of intrauterine transfusion therapy.
Data abstracted included transfusion data, pre-transfusion hemoglobin (Hb) and lowest recorded (nadir) Hb, and maternal and neonatal outcomes.During the study period, 74 patients received transfusion therapy (1.4%).
The process of transfusion therapy begins with the collection of a volume of blood by either whole blood donation or by an apheresis collection procedure.
Thus, it is important to understand the indications for and goals of transfusion therapy and to be aware of the potential side effects of therapy.
Years of unsystematic clinical observations, followed by more carefully designed and in some cases randomized studies, have contributed substantially to our knowledge of transfusion therapy in SCD.
Even highly regulated processes, such as laboratory specimen acquisition and transfusion therapy, use guidelines that may be vague, misunderstood, and hence erratically implemented.
