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It is defined as surveillance procedures covering the whole transfusion chain, from collection of blood and its components to follow-up of recipients, intended to collect and assess information on unexpected or undesirable effects resulting from the therapeutic use of labile blood products and to prevent their occurrence or recurrence (International Haemovigliance Network [IHN], 2012).
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(ii) We included only the studies that used the following serological markers of chronic viral infections: HBsAg for HBV infection, and anti-HCV (tested with enzyme-linked immunosorbent assay, ELISA) or HCV RNA (detected by reverse transfusion polymerase chain reaction (RT PCR) for HCV infection.
The diagnosis was based on family history, transfusion dependence, analysis of globin chains synthesis by HPLC and molecular analysis of mutations.
Because of the prevalence of missing data for transfusion, we performed multiple imputation by chained equations to account for missing data [ 23- 25].
Plasmapheresis technology needs to be available or introduced, including quality-assured testing for transfusion-transmissible infections and an effective cold chain, all of which have been major challenges in the currently affected West African countries.
Conclusion: Analysis by quantitative polymerase chain reaction amplification demonstrated a large fetal-maternal transfusion after elective abortion.
Patients with β-thalassemia major (β-TM) harbor two defective copies of the β-globin chain and present during the first 2 years of life with a severe lifelong transfusion dependent microcytic anemia.
A transfusion?
Policeman Volunteers for Transfusion.
A blood transfusion?
Lucy had needed a transfusion.
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