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Chan, A. M. et al. Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product.
The cellular oncogene c-src and its viral homologue v-src (the transforming gene of Rous sarcoma virus) encode 60-kD cytoplasmic, membrane-associated protein tyrosine kinases.
His major contributions stem from his initial identification, in 1970, of the transforming gene of Rous sarcoma virus, which causes a type of cancer in chickens.
The cellular oncogene c-yes and its viral homologue v-yes (the transforming gene of Yamaguchi 73 and Esh avian sarcoma viruses) encode 62-kilodalton, cytoplasmic, membrane-associated, protein-tyrosine kinases.
My research interests developed out of my initial identification of the transforming gene of the retrovirus Rous sarcoma virus, and the finding that this gene, the v-src gene, is both necessary and sufficient for transformation.
The design of MARQUEE is based on preclinical data, the current understanding of the role of cellular N-methyl-N'-nitroso-guanidine human osteosarcoma (MNNG HOS) transforming gene (MET) in NSCLC, and clinical data from a randomized phase II study.
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Interestingly, PTTG1IP (pituitary tumor transforming gene-binding factor) is a poorly characterized proto-oncogene that has already been implicated in the etiology of thyroid tumors [ 36, 37].
Neuroepithelial transforming gene-1 (Net1) is a guanine nucleotide exchange factor (GEF) that activates Rho family proteins (Symons and Rusk, 2003).
A riboprobe for pituitary tumor-transforming gene 1 (Pttg1) resulted in staining of only a subset of cells in the ONBL at all the stages examined (Figure 6B D).
Pituitary tumor-transforming gene (PTTG) was originally identified in rat pituitary tumors by differential display PCR.
rs2431697 is located on 5q33.3, between pituitary tumor-transforming gene 1 and miR-146a.
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