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This pathway is activated by a variety of stimuli including growth factors, mitogens, transforming agents, and virus infections.
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For example, activation of the neuregulin signaling pathway produces molecules that function as mitogens, differentiation agents and transforming agents in epithelial cells [ 35].
We have shown previously that overexpression of EphB4 in tumour cells is tightly regulated by known transforming agents such as EGFR (Masood et al, 2006) and HER-2/neu (Kumar et al, 2006), and inhibited by tumour suppressors such as p53 (Xia et al, 2006) and PTEN (Xia et al, 2005).
Generosity and humility, more than political consciousness, were the transforming agents in his creative process.
In addition, transforming agents used to immortalize these cell lines may affect cellular functions and impede their use for clinical applications [ 3].
I hope they will inspire us to remind children and youth today that they are not citizens in waiting; they too can be transforming agents for change. .
Whether the expression changes of cytoskeleton-related genes identified here such as coro1C, nrp2, kif23, are specific to DEHP or to cell transforming agents more generally would require further studies.
The concepts of vein nodes and auxins were transformed into agents and markers of free spaces.
When SV40 DNA was employed as the transforming agent for the latter, the transformation rate was no longer raised.
The review indicates that landscape dynamics in the Pyrenees have been greatly controlled by both long term and abrupt climate changes and, since the Middle Holocene, and particularly since Medieval times, by human activities as new transforming agent.
Furthermore, FeCl3 could also act as a crucial transforming agent that converted solid-state B powders to gaseous boron chloride (BCl3) in situ.
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