Sentence examples for transforming activity from inspiring English sources

Mutations in codon 61 resulted in constitutive activation and increased the transforming activity of cells (Der et al, 1986).

The resulting activated Neu receptors have relatively weak transforming activity in comparison with the original V664E mutant allele [39].

To determine whether inhibition of Ras transformation by Stat1 involves p27Kip1, we assessed the transforming activity of the MEFs when endogenous p27Kip1 levels were decreased by shRNA.

Shimomura, T. et al. The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity.

A further twofold reduction in transforming activity was observed with insulated LCR-containing LV.

The E5 proteins of human papillomavirus (HPV) are highly hydrophobic transmembrane proteins that display weak transforming activity.

Furthermore the ligand-independent transforming activity of EGFRvIII is independent of receptor dimerization.

Bap-1 may function in the regulation of c-Bcr and may contribute to the transforming activity of Bcr-Abl in vivo.

Different molecular weight (MW) fractions of UW18 CM were prepared by molecular ultrafiltration, and each fraction was tested for transforming activity.

Moreover, PI3Kβ can be mutated (low incidence) or drive signal downstream of mitogenic GPCRs or facilitate the transforming activity downstream of mutant Rac GTPase.

In addition, Dbl oncogene transforming activity has never been reported for epithelial cells.