Sentence examples for transforming activities from inspiring English sources

In concert with the morphological cell transformation activities of other K-region dihydrodiols of PAHs, these data suggest a new mechanism/pathway for the morphological cell transforming activities of B[a]P and its metabolites.

In summary, this study provides evidence for the DNA damaging and morphological cell transforming activities of the K-region dihydrodiol of B[a]P, in the absence of covalent stable DNA adducts.

Interestingly, the fact that c-Src can restore cytosolic β-catenin while having no effect on cell transforming activities of c-Yes depleted cells suggests that c-Yes may induce additional signalling pathways to ensure neoplastic properties of CRC cells.

IGF1R has potent mitogenic, antiapoptotic, and transforming activities [ 17].

(A ) Antenna-to-leg transforming activities of Nv HoxB and Nv HoxE.

(A ) Antenna-to-leg transforming activities of Nv Hox proteins do not rely on the repression of homothorax (hth ) target gene.

Whereas C-JUN and C-FOS are known as activating proto-oncogenes with transforming activity [ 73, 74], JUND also shows de-activating features [ 68, 73, 75- 77].

Biological studies conducted by Richard Marais and Chris Marshall confirmed that the mutations usually activate the BRAF kinase conferring transforming activity upon it (Davies et al, 2002).

Amplification of ALK, a gene with transforming activity in anaplastic large cell lymphoma was also seen.

Our data show that c-Yes transforming activity is not redundant to that of c-Src, although the latter is predominantly expressed in these tumours.

Recombinant E7 protein with mutated regions showed lower efficiency in transforming activity [ 45].