Exact(22)
These studies, although technically correct, proved misleading as most transformed T cells can be activated by stimulation of the clonotypic T-cell receptor (TCR) alone.
Deep sequencing of the tumor genome showed a highly heterogeneous landscape of genetic perturbations, and transcriptome analysis of transformed T cells further highlighted the heterogeneity of this disease.
Cook HL, Lytle JR, Mischo HE, Li MJ, Rossi JJ, Silva DP, Desrosiers RC, Steitz JA. (2005) Small nuclear RNAs encoded by Herpesvirus saimiri upregulate the expression of genes linked to T cell activation in virally transformed T cells.
We then isolated total RNAs from a number of transformed T cell lines and B cell lines and performed sequencing.
The notion was strengthened by findings showing the critical dependence of transformed T cells' survival on BCL11B expression [22], [23].
We have analyzed the phosphorylation state of Lck and Fyn and TCR signaling in human naïve CD4+ T cells and in the transformed T cell line, Hut-78.
Similar(38)
Here, we compare the role of Oct4 and Nanog, two-core pluripotent TFs, in transformed (t-hPSCs), and normal human pluripotent stem cells (hPSCs).
On the other hand, Ji et al. [46] compared the role of Oct3/4 and Nanog in transformed (t-hPSCs), and normal human pluripotent stem cells (hPSCs).
Increased expression of GluA-2/Os10g0400200 and Os10g0207500, components of T-DNA, were directly derived from the transformed T-DNA.
In our study, harpin Xoo was detected as clustered particles mainly along the cell walls of transformed T-34.
Decreased caspase-10 expression was also shown in adult tumour cell lines, supporting previously reported decreased caspase-10 expression in transformed T- and B-cell lines.
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