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Soto-Reyes, E. & Recillas-Targa, F. Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines.
Furthermore, most TALEN transformed cell lines were found to be genetically homogeneous without the need for re-plating, which greatly facilitates the screening process.
Various studies have already been published on the subject, however, almost all of these studies have been conducted in cancer or transformed cell lines.
Following this, we have determined the modulation of BH3-only transcripts to a variety of apoptotic stimuli, in selected primary and transformed cell lines.
Many transformed cell lines are amenable to SILAC.
Extraordinary activation of PKCα has been identified in transformed cell lines and in several cancers [7 10].
EMT has been frequently observed in transformed cell lines.
Because of these technical issues, we carried out Cyclin T1-depletion experiments in transformed cell lines.
Conventional cytogenetic analysis identified complex clonal chromosome aberrations in all three transformed cell lines.
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We demonstrate that NKp30L and NKp44L are ubiquitously and variably expressed on transformed and non-transformed cell lines.
Through these experiments, we have generated a number of transformed and non-transformed cell lines with well-characterized genetic abnormalities recapitulating various stages of carcinogenesis in Barrett's esophagus.
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