Sentence examples for transformation resistance from inspiring English sources

Exact(11)

Subsequent experiments showed that much (though not all) of the transformation resistance was provided by p19ARF [ 12].

The theory of multistage carcinogenesis and the ensuing notion of transformation resistance of cells as the countdown trigger of carcinogenesis (see above) lay the basis for some assumptions.

As mutagenesis is progressing (and the mutational pyramid grows in width and height), the transformation resistance of the cell is depleted, thus serving as a countdown trigger.

The transformation resistance of normal individuals is evolutionary adjusted in such a way as to postpone tumor appearance to post-reproductive period.

The fact that transformation resistance of cells is not only species-specific but also cell type-specific indicates that genetic as well as epigenetic mechanisms participate in its formation.

If cancer had any unfavorable influence on viability of a species, then its ousting beyond the limits of the species' life span by means of augmentation of the transformation resistance would be easily achieved.

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Similar(49)

How can the colonized mind be open to transformation and resistance given that it is already colonized?

In contrast, PDK1 expression and gene copy number are increased in breast cancer [12], [13], [14] and breast cancer cell lines [15], which is consistent with down-regulation of PDK1 inhibiting cancer cell migration and metastases [16], and over-expression of PDK1 inducing transformation, drug resistance, invasion and tumorigenicity [13], [17], [18].

CIP2A plays an important role in cell proliferation, transformation, drug resistance and maintenance of a malignant cellular phenotype [ 22].

Chromosomal integration of tetO could confer a more stable and transmissible (via natural transformation) antimicrobial resistance phenotype for clone SA, facilitating its persistence in the sheep production environment.

Tumour development and metastasis are complex processes that include transformation, proliferation, resistance to apoptosis, invasion, neovascularisation and metastatic spread (Liotta et al, 1991).

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