Sentence examples for transformation progression from inspiring English sources

In particular, progressive perturbations of the normal apoptotic pathway occur during neoplastic transformation, progression, and metastasis [ 3], and thus apoptosis-related genes are attractive cancer treatment developmental targets [ 4].

In cells undergoing malignant transformation (progression to cancer), telomeres do shorten, but, as the crisis point nears, a formerly quiescent enzyme called telomerase becomes activated.

Since then, nm23/nme genes have been implied into various and critical cell functions, mainly linked to tumor transformation, progression and dissemination [3], [4].

Metabolic alterations constitute a hallmark in cancer cells: They are required for driving transformation, progression and spreading cancer in tissues [16].

The process of malignant transformation, progression and metastasis of melanoma is poorly understood.

However, among these groups, we did not find any significant predictive value for survivals without transformation, progression, and event.

Thus, in the chapter on bone tumours, the authors consider pre-existing conditions and aetiologic factors together and the account of soft tissue tumours concerns benign to malignant transformations, progression from low-grade to high-grade malignancies, and specific chromosomal translocations.

The loss of nuclear TFAP2α expression was associated with malignant transformation and progression of melanoma, indicating that translocation of TFAP2α from the cytoplasm to the nucleus may be disrupted during melanoma progression.

This study describes the predictive value of oral epithelial dysplasia (OED) grading as an indicator for malignant transformation and progression.

The process of developing CM from EM, sometimes termed "transformation" or "progression" occurs in approximately 2 % of persons with EM annually [4, 5].

Our data also suggest a regulatory role of this ectoenzyme in neoplastic transformation and progression of endometrial adenocarcinomas possibly by degrading certain bioactive peptides such as RANTES.