However, Conzelmann et al. [ 16] only provide a general transformation pattern for scaffold proteins with numerous single protein ligands.
KEGG RPAIR is a collection of biochemical structure transformation patterns (RDM patterns) for substrate product pairs (reactant pairs) in KEGG REACTION.
Although several studies have proposed design patterns for model transformation, there is still no accepted common language to express transformation patterns.
The power transformation shows a similar transformation pattern as the log transformation.
The proposed transformation pattern also preserves the hierarchical structure of the transformation matrix.
Peleg and Tu [ 19] have described the application of design patterns for transformation of clinical guidelines from narrative to executable form.
There is also a need to govern (or control) the atomic information system architecture's patterns for business transformation projects; unfortunately an adaptable atomic information system architecture pattern for such projects is inexistent.
This transformation emphasizes significant changes in firing patterns for units with both low- and high baseline firing rates.
We conducted an initial survey to motivate the need for model transformation design patterns and a user study to validate the methodology we propose to solve problems as model transformations based on design patterns.
Note that this transformation allows for uniform quantification of the significant changes in firing patterns for units with both low- and high baseline firing rates.
