Sentence examples for transformation of a cell from inspiring English sources

Viral transformation of a cell starts at the genetic level, followed by changes in the proteome and the metabolome of the host.

Initially chemokines were thought to only play a role in attracting specific leucocytes to a site of injury; nevertheless it has now been shown that they are involved in the neoplastic transformation of a cell, promotion of angiogenesis, tumour clonal expansion and changes in the ECM, and in particular mediate organ specific metastases in cancer [13].

These properties often change substantially after malignant transformation of a cell.

There is biological support that a few key genetic alterations correspond to the malignant transformation of a cell (Renan, 1993).

Cellular differentiation, the transformation of a cell from one identity (i.e., progenitor cells) to another (i.e., progeny cells), can be attributed to the alternation of varying TF complexes.

In particular, how global DNA hypomethylation contributed to the instability of the genome and in the transformation of a cell from normal to disease.

However, the p53 pathway is activated by any cellular stresses that alter the normal cell-cycle progression or can induce mutations of the genome leading to the transformation of a normal cell into a cancerous cell.

Wings with a bs14 mutant posterior compartment exhibited a transformation of all cell types to vein fate - due to a well established requirement for SRF in vein patterning that is independent of Mal (Fig. 1F) [8].

If chronic inflammation, per se, were a sentinel event in the transformation of a normal cell to a cancer cell, one would expect a high incidence of cancer in patients with chronic arthritis, but that is not evident.

tumourigenesis can be regarded as an evolutionary process, in which the transformation of a normal cell into a tumour cell involves a number of limiting genetic and epigenetic events.

The transformation of a normal cell into a cancer cell takes place through a sequence of a small number of discrete genetic events, somatic mutations: thus, cancer can be regarded properly as a genetic disease of somatic cells [ 4, 16].