Plants deficient in these enzymes generated by antisense transformation showed markedly reduced resistance to viral and fungal infection.
Several studies have documented that inhibition of LDHA can reduce cellular transformation and markedly delay tumor formation, indicating that LDHA is required for tumor progression [ 93, 94].
The transformation frequency markedly decreased with an increase in temperature, dropping to 52.84% and 28.93% when the temperature was 28°C and 30°C, respectively.
Decreased activity of LDH-A is reported to reduce cellular transformation, and markedly delayed tumor formation indicating that LDH-A is important for tumor initiation [ 16].
Additional results indicated that the contribution of COX-2 to transformation was markedly attenuated by treatment with either aspirin or celecoxib (Fig. 4E), at a clinically achievable serum concentration.
The pearlite, bainite, and martensite fractions, axial and hoop stresses near the surface, and the degree of distortion calculated using the improved transformation kinetics exhibited markedly better agreement with the measured results than those calculated using the previous transformation kinetics with Bs and Ms held constant.
Urban and agricultural land transformation has encroached markedly on the preferred natural habitat of baboons (1 ), and the 16 remaining troops on the Peninsula have been forced into marginal areas and are geographically isolated from all other baboon populations.
In our study, transformation efficiency increased markedly with the age of the coffee embryogenic culture to reach maximum at seven months of proliferation, and remained at over 90% for several months.
The incidence of polyps increases with age and the risk of malignant transformation of a polyp markedly increases with its diameter.
Reduction of Cr VI) by citric acid alone proceeded slowly, while the addition of iron oxide could markedly accelerate the transformation of Cr VI) to Cr III) with the rate for 50 nm γ-Fe2O3 particles more faster than that for 5 μm α-Fe2O3 particles.
