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This interplay between the p53 and Rb pathways in senescence bypass and transformation has previously been described for H-Ras V12 and indicates that p53 can act downstream of Rb in the prevention of cellular transformation [40], [42].
The formation of a red product during laccase-catalyzed IC transformation has previously been reported and presumably is due to the condensation of two IC molecules [ 31, 32].
Transient transformation has previously been found to be an effective method to study powdery mildew resistance gene function in wheat [ 6, 11, 13, 14].
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It is proposed that their transformation is related to the transformation causing plateau II in experiments with very rapid cooling, a transformation which has previously been proposed to be related to the formation of bainite.
The detailed transformation protocol has previously been described [ 28].
Improvement of transformation efficiency has previously been achieved by overcoming R-M systems [ 14, 15].
Although the requirement for Rac1 in Ras-induced oncogenic transformation has been previously reported [12], [17], there has been no prior demonstration that mutant active Ras increases Rac1 activity in tumors.
The involvement of fibroblasts in the malignant transformation of epithelial cells has previously been documented [ 3, 26- 28].
Most of the proteins in the ETS family are downstream nuclear targets of ras-MAP kinase signaling, and the deregulation of ETS genes results in the malignant transformation of cells [ 24] It has previously been reported that mutant TP53 required ETS1 to synergistically activate the expression of ABCB1.
It's a moment of transformation". Mr Mubarak had previously pledged to quit office after presidential elections due to be held in September.
The formation of complex mosaic alleles has previously been observed after transformation or transduction of homeologous DNA into E. coli.
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